Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456913 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL10438825 | 0.75 | ALDH1A1 (0.43) | ALOX5ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL6976915 | 0.70 | NPC1 (0.51) | ALOX5ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL37520 | 0.69 | MAPT (0.56) | ALOX5ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL7759462 | 0.69 | ALOX5 (0.44) | ALOX5ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1839147 | 0.68 | L3MBTL1 (0.49) | ALOX5ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL17697666 | 0.68 | LMNA (0.47) | ALOX5ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4633787 | 0.68 | MAPT (0.44) | ALDH1A1MAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL8195881 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL8516383 | 0.67 | TSHR (0.52) | ALOX5ALDH1A1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380985-B1 | Esters of 4-aryl-2-halogen imidazol-5-carbonic acid, their preparation and use | BASF AG (DE) | 1993-12-08 | — | — | EP | disclosed |
| EP-0380985-A2 | Esters of 4-aryl-2-halogen imidazol-5-carbonic acid, their preparation and use | BASF Aktiengesellschaft (DE) | 1990-08-08 | — | — | EP | disclosed |