Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517236 | 0.88 | HTR1A (0.43) | HTR1ASTAT3 | |
| SCHEMBL9514280 | 0.87 | HTR1A (0.44) | HTR1A | |
| SCHEMBL9514753 | 0.85 | HTR1A (0.45) | HTR1A | |
| SCHEMBL9517046 | 0.81 | MAPT (0.54) | HTR1ASTAT3 | |
| SCHEMBL9517210 | 0.78 | MAPT (0.42) | HTR1ASTAT3 | |
| SCHEMBL9515163 | 0.77 | STAT3 (0.40) | HTR1ASTAT3 | |
| SCHEMBL9513786 | 0.76 | NPC1 (0.48) | HTR1ASTAT3 | |
| SCHEMBL9514704 | 0.75 | NPC1 (0.47) | HTR1ASTAT3 | |
| SCHEMBL9517325 | 0.74 | LMNA (0.41) | HTR1A | |
| SCHEMBL9516240 | 0.72 | NPC1 (0.48) | HTR1ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5227488-A | AZA SPIRO DECANE AND USE THEREOF IN TREATING CNS DISORDERS | NOVO NORDISK A/S (DK) | 1993-07-13 | — | — | US | claimed |
| EP-0495826-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-29 | — | — | EP | claimed |
| WO-1991004973-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-04-18 | — | — | WO | claimed |
| US-5227488-A | AZA SPIRO DECANE AND USE THEREOF IN TREATING CNS DISORDERS | NOVO NORDISK A/S (DK) | 1993-07-13 | — | — | US | disclosed |
| EP-0495826-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991004973-A1 | INDOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-04-18 | — | — | WO | disclosed |