Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silafluofen SCHEMBL27295 | 0.81 | LTA4H (0.43) | MAPTRAB9AL3MBTL1DRD4KDM4E | |
| Silafluofen SCHEMBL8880052 | 0.81 | LTA4H (0.43) | MAPTRAB9AL3MBTL1DRD4KDM4E | |
| SCHEMBL8538312 | 0.75 | FDFT1 (0.43) | SMN1; SMN2L3MBTL1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL9799431 | 0.75 | NQO1 (0.41) | SMN1; SMN2MAPTRAB9AL3MBTL1KDM4E | |
| Silafluofen SCHEMBL7861197 | 0.74 | KMT2A (0.38) | SMN1; SMN2MAPTRAB9AKMT2A | |
| SCHEMBL6779563 | 0.73 | LTA4H (0.51) | MAPTKMT2A | |
| SCHEMBL1359316 | 0.72 | NQO1 (0.50) | P2RX7MAPTMEN1KMT2ATP53 | |
| SCHEMBL14671446 | 0.70 | GLA (0.47) | SMN1; SMN2GLARAB9AHPGDHTT | |
| SCHEMBL9618130 | 0.70 | NQO1 (0.48) | SMN1; SMN2MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL9654087 | 0.70 | NQO1 (0.48) | SMN1; SMN2MAPTRAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308788-B1 | Process for the preparation of (aryl)-(dimethyl)-(3-(4-fluoro-3-aryloxyphenyl)propyl) silanes | HOECHST AG (DE) | 1993-12-08 | — | — | EP | disclosed |
| US-5117028-A | Catalysis with hexachloroplatinic acid; hydrosilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0479244-A1 | Process for the preparation of 4-ethoxyphenyl-3-arylpropyl-dimethyl silanes | Hoechst Schering AgrEvo GmbH (DE) | 1992-04-08 | — | — | EP | disclosed |
| US-4920212-A | Process for the preparation of (aryl)-(dimethyl)-(3-(4-fluoro-3-aryloxyphenyl)propyl)silanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| EP-0308788-A2 | Process for the preparation of (aryl)-(dimethyl)-(3-(4-fluoro-3-aryloxyphenyl)propyl) silanes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-29 | — | — | EP | disclosed |