Iprofenin

Iprofenin

SCHEMBL486656

CC(C)c1ccc(NC(=O)CN(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.58
CA2 P00918 6/20 0.58
HPGD P15428 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
LMNA P02545 1/20 0.55
RAB9A P51151 2/20 0.55
NPC1 O15118 1/20 0.54
CA12 O43570 2/20 0.52
CA9 Q16790 2/20 0.52
CA4 P22748 2/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
ALDH1A1 P00352 2/20 0.50
ATM Q13315 1/20 0.50
KDM4E B2RXH2 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9514501 0.82 CA1 (0.68) CA1CA2RAB9ACA12CA9
SCHEMBL16980495 0.82 SMN1; SMN2 (0.61) HPGDSMN1; SMN2LMNARAB9ANPC1
SCHEMBL11193183 0.82 SMN1; SMN2 (0.65) HPGDSMN1; SMN2LMNARAB9ANPC1
SCHEMBL9974560 0.80 CA1 (0.64) CA1CA2CA12CA9CA4
SCHEMBL9515833 0.79 CA2 (0.63) CA1CA2CA12CA9CA4
SCHEMBL9945977 0.79 RAB9A (0.68) CA1CA2HPGDSMN1; SMN2RAB9A
SCHEMBL2033654 0.79 CA1 (0.46) CA1CA2CA4ALOX15TSHR
SCHEMBL11207364 0.78 SMN1; SMN2 (0.65) HPGDSMN1; SMN2LMNARAB9ANPC1
SCHEMBL15499792 0.78 CA1 (0.75) CA1CA2LMNACA12CA9
SCHEMBL486751 0.78 CA1 (0.58) CA1CA2SMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
US-20230201386-A1 PRODUCING RADIOPHARMACEUTICAL COLD KITS WITHOUT LYOPHILIZATION THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA 2023-06-29 US claimed
CN-104666246-A Orally Bioavailable Lipid-based Constructs SDG INC AN OHIO CORPRATION 2015-06-03 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal SDG, INC. (US) 2011-06-09 US claimed
WO-2011022396-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2011-02-24 WO claimed
US-7871641-B2 Hepatocyte-targeting vehicle for delivery of glargine insulin to a mammal SDG, INC. (US) 2011-01-18 US claimed
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal SDG, INC. 2006-10-05 US claimed
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. 2006-10-05 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
CN-1264310-A Polymer based pharmaceutical compositions for targeted delivery of biologically active agents SDG INC (US) 2000-08-23 CN claimed
CN-1261791-A Targeted liposomal constructs for diagnostic and therapeutic uses SDG INC (US) 2000-08-02 CN claimed
EP-0999855-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, Inc. (US) 2000-05-17 EP claimed
US-6063400-A CARRIER; DIAGNOSTIC OR THERAPEUTIC AGENT AND SEQUESTERING AGENT SDG, INC. (US) 2000-05-16 US claimed
WO-1999004824-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, INC. (US) 1999-02-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 CA1 2966/4885CA2 2040/4885HPGD 1531/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 CA1 3267/4885CA2 698/4885HPGD 2154/4885
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal INSR, GPR119, GCG CA1 1841/4885CA2 1696/4885HPGD 1849/4885
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal INSR, IAPP, GPR119 CA1 2697/4885CA2 3633/4885HPGD 3818/4885
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal INSR, INSRR, IAPP CA1 895/4885CA2 1276/4885HPGD 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.