SCHEMBL9515833

SCHEMBL9515833

O=C(O)CN(CC(=O)O)CC(=O)Nc1ccc(C(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 12/20 0.63
CA1 P00915 11/20 0.63
CA12 O43570 3/20 0.56
CA9 Q16790 3/20 0.56
CA4 P22748 3/20 0.55
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEP1B Q16820 1/20 0.49
ALDH1A1 P00352 2/20 0.47
GAA P10253 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
LTA4H P09960 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9263159 0.85 ALDH1A1 (0.67) CA2CA1CA12CA9TDP1
SCHEMBL9974560 0.84 CA1 (0.64) CA2CA1CA12CA9CA4
SCHEMBL9514501 0.83 CA1 (0.68) CA2CA1CA12CA9CA4
SCHEMBL15499792 0.82 CA1 (0.75) CA2CA1CA12CA9CA4
SCHEMBL1066727 0.81 MAPT (0.59) CA2CA1CA12CA9ALDH1A1
SCHEMBL2843886 0.80 CA12 (0.56) CA2CA1CA12CA9TSHR
SCHEMBL9617679 0.79 BCHE (0.62) CA2CA1CA12CA9CA4
SCHEMBL486751 0.79 CA1 (0.58) CA2CA1CA12CA9CA4
Iprofenin SCHEMBL486656 0.79 CA1 (0.58) CA2CA1CA12CA9CA4
SCHEMBL3911049 0.78 CA12 (0.54) CA2CA1CA12CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0290041-B1 Radioactive metal chelates of dipyridoxyl phosphate NYCOMED SALUTAR INC (US) 1993-12-08 EP disclosed
US-4842845-A Radioactive metal chelates for dipyridoxyl phosphate SALUTAR, INC. (US) 1989-06-27 US disclosed
EP-0290041-A2 Radioactive metal chelates of dipyridoxyl phosphate NYCOMED SALUTAR, INC. (US) 1988-11-09 EP disclosed