Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | FABP6 | P51161 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513674 | 0.87 | KDM4E (0.59) | ALDH1A1KDM4ESMN1; SMN2MAPK1PKM | |
| SCHEMBL1108658 | 0.81 | KDM4E (0.62) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL11078057 | 0.81 | SLC6A7 (0.70) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL9763711 | 0.80 | PKM (0.74) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL9731153 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL1596692 | 0.78 | PKM (0.72) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL13149233 | 0.78 | KDM4E (0.71) | ALDH1A1KDM4ESMN1; SMN2MAPTMEN1 | |
| SCHEMBL14276896 | 0.77 | MAP4K4 (0.51) | ALDH1A1GAA | |
| SCHEMBL12225719 | 0.76 | MAPK1 (0.69) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14590536 | 0.76 | MAPK1 (0.69) | ALDH1A1MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384370-B1 | Substituted pyrimidine derivatives, process for their preparation, and their use as tool | HOECHST AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-5138058-A | Diabetic screening | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0384370-A1 | Substituted pyrimidine derivatives, process for their preparation, and their use as tool | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |