Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 6/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516262 | 0.88 | GRM5 (0.40) | CASP3SLC6A9SLC6A5GRM5HDAC6 | |
| SCHEMBL9518019 | 0.87 | MEN1 (0.39) | CASP3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9517174 | 0.87 | HDAC1 (0.39) | CASP3SLC6A9HDAC6HDAC5HDAC3 | |
| SCHEMBL9519643 | 0.87 | GRM5 (0.39) | CASP3SLC6A9SLC6A5GRM5HDAC6 | |
| SCHEMBL9516708 | 0.86 | SLC6A9 (0.37) | CASP3SLC6A9SLC6A5MEN1NPC1 | |
| SCHEMBL9515545 | 0.84 | HDAC6 (0.36) | CASP3SLC6A9SLC6A5MEN1NPC1 | |
| SCHEMBL9515835 | 0.84 | LMNA (0.39) | CASP3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9515748 | 0.83 | P4HTM (0.39) | CASP3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9517229 | 0.82 | POLB (0.38) | CASP3RAB9AL3MBTL1GRM5HDAC6 | |
| SCHEMBL9516974 | 0.81 | EGFR (0.44) | CASP3MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |