Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ledazerol SCHEMBL8989308 | 0.78 | GABRA1 (0.33) | KDM4ELMNA | |
| SCHEMBL1482608 | 0.76 | AMY1A (0.61) | SHBGAMY1ACYP2C9CYP2C19HIF1A | |
| SCHEMBL210506 | 0.76 | AMY1A (0.61) | SHBGAMY1ACYP2C9CYP2C19HIF1A | |
| SCHEMBL29400422 | 0.76 | AMY1A (0.61) | SHBGAMY1ACYP2C9CYP2C19HIF1A | |
| SCHEMBL187792 | 0.74 | SHBG (0.52) | SHBGAMY1ACYP2C9CYP2C19HIF1A | |
| SCHEMBL8733376 | 0.73 | SHBG (0.60) | SHBGAMY1ACYP2C9CYP2C19HIF1A | |
| SCHEMBL10405987 | 0.73 | GAA (0.42) | AMY1AKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL11051541 | 0.72 | MPO (0.33) | — | |
| SCHEMBL11100874 | 0.71 | SHBG (0.44) | SHBG | |
| SCHEMBL10406697 | 0.70 | HTR1D (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269599-B1 | Substituted 1H-imidazoles | UCB SA (BE) | 1993-12-15 | — | — | EP | disclosed |
| US-4814343-A | ANTIISCHEMIC | U C B, S.A. (BE) | 1989-03-21 | — | — | US | disclosed |
| EP-0269599-A2 | Substituted 1H-imidazoles | U C B, S.A. (BE) | 1988-06-01 | — | — | EP | disclosed |