Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520830 | 0.79 | KMT2A (0.41) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL10408862 | 0.73 | CHRM2 (0.44) | CHRM2CHRM3 | |
| SCHEMBL8400245 | 0.73 | CHRM2 (0.68) | CHRM2CHRM3 | |
| SCHEMBL13490375 | 0.70 | RAB9A (0.46) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL9624898 | 0.67 | MAPT (0.44) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL16299538 | 0.67 | ALDH1A1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL2420231 | 0.66 | CHRM3 (0.58) | CHRM2CHRM3ALDH1A1KMT2ANPSR1 | |
| SCHEMBL11195135 | 0.66 | ALDH1A1 (0.48) | ALDH1A1KMT2ANPSR1 | |
| SCHEMBL171232 | 0.65 | CDK12 (0.42) | ALDH1A1KMT2A | |
| SCHEMBL3036992 | 0.64 | ATM (0.48) | ALDH1A1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296721-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-23 | — | — | EP | disclosed |