Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519404 | 0.79 | CHRM2 (0.46) | KMT2AALDH1A1NPSR1 | |
| SCHEMBL10408544 | 0.74 | CHRM1 (0.33) | ALDH1A1CHRM1MAPK1SMN1; SMN2 | |
| SCHEMBL13490375 | 0.68 | RAB9A (0.46) | KMT2AALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL9624898 | 0.68 | MAPT (0.44) | KMT2AALDH1A1NPSR1MAPTABL1 | |
| SCHEMBL16299538 | 0.68 | ALDH1A1 (0.43) | KMT2AALDH1A1MAPTPOLBLMNA | |
| SCHEMBL2420231 | 0.67 | CHRM3 (0.58) | KMT2AALDH1A1NPSR1CHRM1MAPT | |
| SCHEMBL11195135 | 0.67 | ALDH1A1 (0.48) | KMT2AALDH1A1NPSR1CHRM1MAPT | |
| SCHEMBL171232 | 0.66 | CDK12 (0.42) | KMT2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL9456814 | 0.65 | MAPT (0.40) | KMT2AALDH1A1NPSR1CHRM1MAPT | |
| SCHEMBL9456810 | 0.65 | MAPT (0.40) | KMT2AALDH1A1NPSR1CHRM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296721-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-23 | — | — | EP | disclosed |