Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519296 | 0.91 | OPRK1 (0.40) | ALDH1A1LMNATDP1KDM4EMAPT | |
| SCHEMBL9519209 | 0.85 | HTT (0.40) | ALDH1A1LMNATDP1MAPTSMN1; SMN2 | |
| SCHEMBL9520871 | 0.83 | CCR5 (0.36) | ALDH1A1LMNATDP1KDM4EMAPT | |
| SCHEMBL6400164 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1KDM4EMAPT | |
| SCHEMBL9854866 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1KDM4EMAPT | |
| SCHEMBL562016 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1KDM4EMAPT | |
| SCHEMBL10364355 | 0.81 | TDP1 (0.43) | ALDH1A1TDP1MAPTHTTATM | |
| SCHEMBL6398540 | 0.81 | TDP1 (0.43) | ALDH1A1TDP1MAPTHTTATM | |
| SCHEMBL8759638 | 0.81 | TDP1 (0.43) | ALDH1A1TDP1MAPTHTTATM | |
| SCHEMBL9363991 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1LMNATDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |