Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521948 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9521802 | 0.84 | SIGMAR1 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Ambasilide SCHEMBL427931 | 0.84 | HSD11B1 (0.53) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9521359 | 0.84 | KMT2A (0.58) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| Ambasilide SCHEMBL246531 | 0.84 | HSD11B1 (0.53) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL13149337 | 0.81 | ALDH1A1 (0.70) | ALDH1A1FAAHSMN1; SMN2KDM4ETSHR | |
| SCHEMBL9520996 | 0.81 | CYP2D6 (0.61) | ALDH1A1FAAHCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9523517 | 0.81 | ALDH1A1 (0.51) | ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL10409272 | 0.81 | SIGMAR1 (0.68) | FAAHPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL9520394 | 0.80 | HTT (0.50) | ALDH1A1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308843-B1 | Bispidin derivatives as class III antiarrhythmics | BASF AG (DE) | 1993-12-15 | — | — | EP | disclosed |
| US-4959373-A | Bispidine derivatives as class III antiarrhythmic agents | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| EP-0308843-A2 | Bispidin derivatives as class III antiarrhythmics | BASF Aktiengesellschaft (DE) | 1989-03-29 | — | — | EP | disclosed |