Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522691 | 0.85 | CTSD (0.39) | CTSDGUSBLMNACTNNB1WNT3A | |
| SCHEMBL1260120 | 0.74 | MAPT (0.40) | CTSDGUSBLMNACTNNB1WNT3A | |
| SCHEMBL9522835 | 0.73 | CTSD (0.52) | CTSDGUSBLMNAKDM4E | |
| SCHEMBL20556851 | 0.70 | F2R (0.54) | CTSDGUSBEGFR | |
| SCHEMBL9523358 | 0.70 | CTSD (0.53) | CTSDGUSBKDM4E | |
| SCHEMBL9522731 | 0.68 | LMNA (0.58) | CTSDGUSBLMNAKDM4E | |
| SCHEMBL9524921 | 0.67 | LMNA (0.53) | CTSDGUSBLMNAKDM4E | |
| SCHEMBL2334167 | 0.66 | CES2 (0.52) | LMNACTNNB1WNT3AEGFRCES2 | |
| SCHEMBL802201 | 0.65 | KDM4E (0.57) | KDM4E | |
| SCHEMBL208041 | 0.65 | CES2 (0.59) | LMNACTNNB1WNT3ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129409-B1 | Thiazolo - and thiazinobenzimidazoles | WYETH JOHN & BROTHER LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-4873237-A | ANTIULCER AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1989-10-10 | — | — | US | disclosed |
| EP-0129409-A2 | Thiazolo - and thiazinobenzimidazoles | JOHN WYETH & BROTHER LIMITED (GB) | 1984-12-27 | — | — | EP | disclosed |