Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520994 | 0.88 | L3MBTL1 (0.38) | L3MBTL1PKMGPBAR1POLBKMT2A | |
| SCHEMBL24151458 | 0.86 | L3MBTL1 (0.41) | L3MBTL1PKMGPBAR1POLBKMT2A | |
| SCHEMBL22745804 | 0.82 | MAPT (0.36) | KMT2AALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL9521057 | 0.81 | GAA (0.38) | CYP1A2MAPTCYP2C9TP53LMNA | |
| SCHEMBL9350427 | 0.81 | NOTUM (0.40) | L3MBTL1PKMPOLBKMT2AALDH1A1 | |
| SCHEMBL9468954 | 0.79 | MAPT (0.35) | PKMPOLBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL7547124 | 0.79 | CYP1A2 (0.33) | POLBKMT2ACYP1A2MAPTCYP2C9 | |
| SCHEMBL9567022 | 0.79 | TSHR (0.35) | L3MBTL1POLBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL9499007 | 0.78 | CYP1A2 (0.35) | KMT2ACYP1A2MAPTCYP2C9TSHR | |
| SCHEMBL9423183 | 0.78 | ALDH1A1 (0.36) | L3MBTL1KMT2AALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |