Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520394 | 0.85 | HTT (0.50) | ALDH1A1GRIN2BHTTCHRNB2CHRNB4 | |
| Ambasilide SCHEMBL6385706 | 0.83 | ALDH1A1 (0.47) | SMN1; SMN2LMNAALDH1A1MAPK1MEN1 | |
| SCHEMBL9521948 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2LMNAALDH1A1MAPK1CHRNB2 | |
| SCHEMBL7034748 | 0.82 | HTT (0.53) | SMN1; SMN2LMNAALDH1A1MAPK1HPGD | |
| Hydrochloric Acid SCHEMBL8781292 | 0.82 | LMNA (0.70) | PKMSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL9521802 | 0.80 | SIGMAR1 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| Ambasilide SCHEMBL246531 | 0.80 | HSD11B1 (0.53) | SMN1; SMN2LMNAALDH1A1MAPK1CA12 | |
| SCHEMBL9521359 | 0.80 | KMT2A (0.58) | SMN1; SMN2LMNAALDH1A1MAPK1HPGD | |
| Ambasilide SCHEMBL427931 | 0.80 | HSD11B1 (0.53) | SMN1; SMN2LMNAALDH1A1MAPK1CA12 | |
| SCHEMBL9520996 | 0.80 | CYP2D6 (0.61) | PKMSMN1; SMN2LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308843-B1 | Bispidin derivatives as class III antiarrhythmics | BASF AG (DE) | 1993-12-15 | — | — | EP | disclosed |