Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TPMT | P51580 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049040 | 0.85 | CES2 (0.35) | TTRTSHRALDH1A1NPC1RAB9A | |
| SCHEMBL10644194 | 0.80 | TTR (0.62) | TTRTSHRALDH1A1MAPTSRD5A2 | |
| SCHEMBL10921198 | 0.79 | TTR (0.48) | TTRTSHRALDH1A1MAPTSRD5A2 | |
| SCHEMBL983196 | 0.79 | HPGD (0.46) | TTRTSHRALDH1A1SRD5A2KMO | |
| SCHEMBL28319759 | 0.78 | CA5A (0.46) | TTRTSHRALDH1A1MAPTTPMT | |
| SCHEMBL27864269 | 0.78 | HTT (0.44) | TTRTSHRALDH1A1MAPTKDM4E | |
| SCHEMBL11184770 | 0.78 | TTR (0.48) | TTRTSHRALDH1A1MAPT | |
| SCHEMBL4903616 | 0.77 | TTR (0.65) | TTRTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL104060 | 0.77 | ALDH1A1 (0.54) | TTRTSHRALDH1A1MAPTSRD5A2 | |
| SCHEMBL11818428 | 0.77 | APEX1 (0.41) | TTRTSHRALDH1A1MAPTTPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211598-B1 | Pesticidal compounds | WELLCOME FOUND (GB) | 1993-12-15 | — | — | EP | disclosed |
| US-5098929-A | Insecticides, insect attractants, fungicides or oxidase inhibitors | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |
| EP-0211598-A2 | Pesticidal compounds | ROUSSEL-UCLAF (FR) | 1987-02-25 | — | — | EP | disclosed |