Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528013 | 0.91 | HPGD (0.46) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL9524939 | 0.88 | MEN1 (0.48) | CYP3A4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9527921 | 0.88 | TMPRSS4 (0.42) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9527660 | 0.86 | ALDH1A1 (0.50) | ALDH1A1FAAHCYP3A4MAPK1GAA | |
| SCHEMBL9524847 | 0.83 | MAPT (0.42) | ALDH1A1FAAHCYP3A4MAPK1GAA | |
| SCHEMBL9524848 | 0.83 | MEN1 (0.47) | ALDH1A1MAPK1MEN1KMT2ANPC1 | |
| SCHEMBL9523908 | 0.82 | HPGD (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9524819 | 0.82 | SORT1 (0.47) | ALDH1A1MAPK1GAAKMT2ANPC1 | |
| SCHEMBL9527538 | 0.81 | KMT2A (0.47) | FAAHGAAMEN1KMT2ARAB9A | |
| SCHEMBL9524888 | 0.81 | MEN1 (0.49) | ALDH1A1MAPK1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |