Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527748 | 0.86 | SMN1; SMN2 (0.54) | MAPTALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL9524870 | 0.85 | CSF1R (0.45) | MAPTKDM4ETHRBRECQLALDH1A1 | |
| SCHEMBL9527921 | 0.85 | TMPRSS4 (0.42) | MAPTGAAHTTSMN1; SMN2LMNA | |
| SCHEMBL9525680 | 0.84 | HTT (0.43) | MAPTKDM4ETHRBRECQLALDH1A1 | |
| SCHEMBL9527660 | 0.84 | ALDH1A1 (0.50) | MAPTKDM4ETHRBRECQLALDH1A1 | |
| SCHEMBL9525703 | 0.84 | RAB9A (0.43) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL9524849 | 0.83 | ALDH1A1 (0.46) | MAPTTHRBALDH1A1GAAHTT | |
| SCHEMBL9527439 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9525587 | 0.79 | ADORA3 (0.47) | MAPTKDM4ETHRBRECQLCXCR2 | |
| SCHEMBL9525091 | 0.78 | RAB9A (0.41) | MAPTKDM4EALDH1A1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |