Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | FADS1 | O60427 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524939 | 0.92 | MEN1 (0.48) | MEN1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL9528013 | 0.91 | HPGD (0.46) | MEN1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL9524715 | 0.91 | MEN1 (0.43) | MEN1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL9524870 | 0.88 | CSF1R (0.45) | KMT2ARAB9AMAPTALDH1A1HTT | |
| SCHEMBL9523908 | 0.86 | HPGD (0.46) | MEN1KMT2ARAB9AFADS1MAPT | |
| SCHEMBL9527538 | 0.85 | KMT2A (0.47) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL9525091 | 0.85 | RAB9A (0.41) | MEN1KMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL9527921 | 0.83 | TMPRSS4 (0.42) | MEN1KMT2ARAB9AMAPTLMNA | |
| SCHEMBL9524849 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2ARAB9AMAPTHPGD | |
| SCHEMBL9525178 | 0.82 | NPC1 (0.43) | MEN1KMT2ARAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |