Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 8/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524819 | 0.87 | SORT1 (0.47) | RAB9ANPC1GBA1GRM5TP53 | |
| SCHEMBL9525788 | 0.85 | ALDH1A1 (0.49) | RAB9ANPC1GBA1GRM5TP53 | |
| SCHEMBL9525669 | 0.83 | NPC1 (0.44) | RAB9ANPC1TP53MAPTMEN1 | |
| SCHEMBL9525594 | 0.81 | GRM5 (0.54) | RAB9ANPC1GBA1GRM5TP53 | |
| SCHEMBL9524715 | 0.81 | MEN1 (0.43) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL9524870 | 0.80 | CSF1R (0.45) | RAB9ANPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL9525091 | 0.79 | RAB9A (0.41) | RAB9ANPC1TP53ALDH1A1MAPT | |
| SCHEMBL9524848 | 0.77 | MEN1 (0.47) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL9525703 | 0.74 | RAB9A (0.43) | RAB9ANPC1TP53ALDH1A1MAPT | |
| SCHEMBL9524939 | 0.74 | MEN1 (0.48) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |