Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524870 | 0.93 | CSF1R (0.45) | RAB9AMAPTGAAKDM4EFAAH | |
| SCHEMBL9527538 | 0.90 | KMT2A (0.47) | RAB9AMAPTGAAKDM4EFAAH | |
| SCHEMBL9524715 | 0.89 | MEN1 (0.43) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL9524999 | 0.87 | RAB9A (0.44) | RAB9AMAPTGAAKDM4EFAAH | |
| SCHEMBL9524848 | 0.85 | MEN1 (0.47) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL9525669 | 0.81 | NPC1 (0.44) | RAB9AMAPTGAAKDM4EKMT2A | |
| SCHEMBL9524939 | 0.81 | MEN1 (0.48) | RAB9AMAPTKMT2AMEN1NPC1 | |
| SCHEMBL9524868 | 0.79 | RAB9A (0.46) | RAB9AMAPTKMT2AMEN1TP53 | |
| SCHEMBL9525178 | 0.79 | NPC1 (0.43) | RAB9AMAPTGAAKDM4EKMT2A | |
| SCHEMBL9524847 | 0.78 | MAPT (0.42) | RAB9AMAPTGAAKDM4EFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |