Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524715 | 0.91 | MEN1 (0.43) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9524939 | 0.87 | MEN1 (0.48) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9524999 | 0.86 | RAB9A (0.44) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9525680 | 0.86 | HTT (0.43) | RAB9AKMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9527660 | 0.86 | ALDH1A1 (0.50) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9527700 | 0.86 | DDX3X (0.44) | KDM4ESMN1; SMN2ALDH1A1MAPTCYP1A2 | |
| SCHEMBL9523908 | 0.86 | HPGD (0.46) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9525725 | 0.86 | KMT2A (0.49) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL9524899 | 0.85 | MAPT (0.50) | RAB9AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9524870 | 0.84 | CSF1R (0.45) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |