Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.40 |
| ▸ | PRKCG | P05129 | 3/20 | 0.40 |
| ▸ | PRKCB | P05771 | 3/20 | 0.40 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | PRKCH | P24723 | 3/20 | 0.40 |
| ▸ | PRKCI | P41743 | 3/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | PRKACG | P22612 | 2/20 | 0.40 |
| ▸ | PRKACB | P22694 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524780 | 0.84 | FLT3 (0.43) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9525433 | 0.73 | EPHX1 (0.45) | NPY5RSMN1; SMN2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL9525706 | 0.73 | CYP1A2 (0.41) | SMN1; SMN2ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL9525362 | 0.73 | BLM (0.43) | MAPK1CYP3A4SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL9524919 | 0.72 | HTT (0.51) | EGFRMAPK1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9525284 | 0.72 | ALDH1A1 (0.40) | EGFRMAPK1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9525530 | 0.72 | HTT (0.46) | EGFRMAPK1CYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9524016 | 0.71 | ALDH1A1 (0.41) | SMN1; SMN2KDM4EALDH1A1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL9528526 | 0.71 | SLC6A9 (0.38) | P2RX7NPY5RCYP3A4SCN1ASCN2A | |
| SCHEMBL9525975 | 0.71 | SMN1; SMN2 (0.43) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |