Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524847 | 0.86 | MAPT (0.42) | SMN1; SMN2ALDH1A1HTTGAALMNA | |
| SCHEMBL9525121 | 0.85 | FLT3 (0.49) | SMN1; SMN2ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL9524933 | 0.84 | NPC1 (0.48) | SMN1; SMN2ALDH1A1GAALMNARAB9A | |
| SCHEMBL9524870 | 0.83 | CSF1R (0.45) | SMN1; SMN2ALDH1A1HTTGAACSF1R | |
| SCHEMBL9527921 | 0.83 | TMPRSS4 (0.42) | SMN1; SMN2HTTGAALMNARAB9A | |
| SCHEMBL9524784 | 0.83 | TACR3 (0.46) | SMN1; SMN2ALDH1A1GAALMNARAB9A | |
| SCHEMBL9525680 | 0.82 | HTT (0.43) | SMN1; SMN2ALDH1A1HTTGAARAB9A | |
| SCHEMBL9524233 | 0.81 | DHODH (0.54) | SMN1; SMN2ALDH1A1HTTLMNARAB9A | |
| SCHEMBL9525091 | 0.76 | RAB9A (0.41) | SMN1; SMN2ALDH1A1HTTGAACSF1R | |
| SCHEMBL9528013 | 0.75 | HPGD (0.46) | ALDH1A1HTTLMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |