Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GSR | P00390 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527439 | 0.87 | SMN1; SMN2 (0.43) | NPC1LMNAHPGDSMN1; SMN2RAB9A | |
| SCHEMBL9524448 | 0.85 | NCEH1 (0.46) | TACR3NPC1RAB9A | |
| SCHEMBL9524845 | 0.84 | PLA2G2A (0.41) | PLA2G2AALDH1A1RAB9A | |
| SCHEMBL9525182 | 0.84 | GABRP (0.42) | KMT2AGSRTP53PLA2G2ATAAR1 | |
| SCHEMBL9527748 | 0.83 | SMN1; SMN2 (0.54) | TACR3MEN1KMT2AEGFRNPC1 | |
| SCHEMBL9523879 | 0.82 | GSK3B (0.53) | TACR3HPGDSMEN1KMT2AKDM4E | |
| SCHEMBL9524933 | 0.77 | NPC1 (0.48) | MEN1KMT2AKDM4ENPC1TP53 | |
| SCHEMBL9524931 | 0.76 | FAAH (0.44) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL9523698 | 0.75 | RAB9A (0.49) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL9525121 | 0.73 | FLT3 (0.49) | MEN1KMT2AKDM4ENPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |