Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527618 | 0.93 | PKM (0.38) | PKMMAPK1KMT2ALMNAALDH1A1 | |
| SCHEMBL9527715 | 0.87 | MAPT (0.35) | KMT2ALMNAALDH1A1RAB9ANPSR1 | |
| SCHEMBL9529753 | 0.87 | CHRNB2 (0.39) | PKMKMT2AALDH1A1RAB9ATSHR | |
| Diethylamine SCHEMBL9527582 | 0.85 | RAB9A (0.37) | PKMMAPK1KMT2AALDH1A1RAB9A | |
| SCHEMBL9530047 | 0.84 | MAPT (0.34) | PKMKMT2AALDH1A1RAB9ANPSR1 | |
| SCHEMBL9528551 | 0.83 | POLB (0.38) | LMNAALDH1A1RAB9ANPSR1POLB | |
| SCHEMBL10367949 | 0.83 | METAP1 (0.35) | KMT2ALMNAALDH1A1TSHRMAPT | |
| SCHEMBL9528699 | 0.83 | HTT (0.39) | MAPK1KMT2AALDH1A1RAB9ANPSR1 | |
| SCHEMBL9528238 | 0.82 | POLB (0.37) | KMT2ALMNAALDH1A1RAB9ANPSR1 | |
| Phosphoric Acid SCHEMBL10367955 | 0.82 | GAA (0.36) | KMT2ALMNARAB9ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | claimed |