Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527810 | 0.87 | PKM (0.39) | MAPTRAB9ANPSR1ALDH1A1LMNA | |
| SCHEMBL9529753 | 0.85 | CHRNB2 (0.39) | RAB9AALDH1A1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL9530047 | 0.82 | MAPT (0.34) | MAPTRAB9ANPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL9528551 | 0.81 | POLB (0.38) | RAB9ANPSR1ALDH1A1LMNAKLK7 | |
| SCHEMBL10367949 | 0.81 | METAP1 (0.35) | MAPTBCDIN3DALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9528238 | 0.80 | POLB (0.37) | PRSS1CTSGCTRB1CMA1RAB9A | |
| SCHEMBL9527618 | 0.80 | PKM (0.38) | PRSS1CTSGCTRB1CMA1RAB9A | |
| Phosphoric Acid SCHEMBL10367955 | 0.80 | GAA (0.36) | MAPTRAB9ANPSR1LMNAMEN1 | |
| SCHEMBL9528360 | 0.80 | RAB9A (0.36) | RAB9ANPSR1ALDH1A1LMNAMEN1 | |
| SCHEMBL9527699 | 0.79 | TACR3 (0.40) | PRSS1CTSGCTRB1CMA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | claimed |
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | disclosed |