Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407004 | 0.89 | TSHR (0.43) | SMN1; SMN2KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL9528465 | 0.86 | ALDH1A1 (0.41) | SMN1; SMN2KMT2ATSHRALDH1A1L3MBTL1 | |
| SCHEMBL9527691 | 0.86 | TSHR (0.45) | SMN1; SMN2KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL9530012 | 0.80 | KDM4E (0.42) | SMN1; SMN2KMT2AGFERTSHRLMNA | |
| SCHEMBL9529021 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2KMT2ALMNAALDH1A1NPSR1 | |
| SCHEMBL9529174 | 0.79 | LTA4H (0.39) | SMN1; SMN2KMT2AGFERLMNAALDH1A1 | |
| SCHEMBL10406930 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL9528114 | 0.76 | CYP2C9 (0.39) | SMN1; SMN2KMT2ATSHRLMNAALDH1A1 | |
| SCHEMBL10407326 | 0.76 | CYP2C19 (0.47) | SMN1; SMN2LMNAALDH1A1NPSR1MAPT | |
| SCHEMBL9532085 | 0.74 | CYP11B1 (0.45) | SMN1; SMN2KMT2ATSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |