Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527584 | 0.90 | LMNA (0.43) | LTA4HRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9529212 | 0.88 | MAPT (0.44) | LTA4HRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9529148 | 0.87 | GLA (0.45) | SMN1; SMN2NPC1ALDH1A1LMNACYP4F2 | |
| SCHEMBL9528779 | 0.83 | KDM4E (0.44) | KCNH2RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9528175 | 0.79 | SMN1; SMN2 (0.40) | RAB9ASMN1; SMN2NPC1ALDH1A1NPSR1 | |
| SCHEMBL9529601 | 0.78 | SLC2A1 (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL9530556 | 0.77 | MAPT (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL9529759 | 0.76 | KMT2A (0.43) | SMN1; SMN2NPC1LMNACYP4F2CYP4A11 | |
| SCHEMBL9529150 | 0.73 | CYP4F2 (0.41) | RAB9ASMN1; SMN2NPC1ALDH1A1NPSR1 | |
| SCHEMBL9529177 | 0.73 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1NPSR1LMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |