Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529221 | 0.81 | PTGER4 (0.41) | NPC1RAB9AMAPTKDM4EPTGER4 | |
| SCHEMBL9528032 | 0.78 | CYP1A1 (0.45) | MAPTKDM4ELMNAPTGER4PTGER3 | |
| SCHEMBL9532029 | 0.77 | KDM4E (0.42) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL23366565 | 0.76 | KDM4E (0.49) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL9529562 | 0.74 | KDM4E (0.42) | NPC1RAB9AKDM4ELMNAL3MBTL1 | |
| SCHEMBL9529150 | 0.73 | CYP4F2 (0.41) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL9529276 | 0.70 | ALDH1A1 (0.46) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL9532053 | 0.70 | NPC1 (0.43) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL9530012 | 0.70 | KDM4E (0.42) | NPC1RAB9AMAPTKDM4ELMNA | |
| SCHEMBL1365894 | 0.70 | KDM4E (0.63) | NPC1RAB9AMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |