Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530556 | 0.91 | MAPT (0.43) | LMNASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9529759 | 0.89 | KMT2A (0.43) | LMNASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9529174 | 0.87 | LTA4H (0.39) | LMNASMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL9528779 | 0.81 | KDM4E (0.44) | LMNASMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL9527691 | 0.80 | TSHR (0.45) | LMNASMN1; SMN2POLBMAPTNPC1 | |
| SCHEMBL9531938 | 0.79 | TBXA2R (0.46) | TSHRMEN1KMT2A | |
| SCHEMBL9527584 | 0.77 | LMNA (0.43) | LMNASMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL9532132 | 0.76 | KMT2A (0.51) | CYP2C9USP2ALDH1A1KMT2A | |
| SCHEMBL9528579 | 0.76 | ALDH1A1 (0.53) | LMNASMN1; SMN2MAPTNPC1TSHR | |
| SCHEMBL9528361 | 0.76 | ALDH1A1 (0.50) | LMNASMN1; SMN2MAPTNPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |