Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700651 | 0.82 | MAPT (0.35) | CYP2C9MOGAT2MAPTESR2HSD17B10 | |
| SCHEMBL9525926 | 0.82 | CYP2C9 (0.31) | CYP2C9MOGAT2MAPTALDH1A1KDM4E | |
| SCHEMBL9528770 | 0.78 | KDM4E (0.48) | MAPTESR2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL9701582 | 0.77 | GCGR (0.39) | CYP2C9MOGAT2PDE5AMAPTHSD17B10 | |
| SCHEMBL9701708 | 0.76 | PDE3B (0.33) | CYP2C9MOGAT2MAPTESR2HSD17B10 | |
| SCHEMBL9700644 | 0.76 | PDE5A (0.38) | PDE5AMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL9525805 | 0.75 | CDC7 (0.36) | CYP2C9MOGAT2MAPTKDM4E | |
| SCHEMBL9525834 | 0.75 | KDM4E (0.44) | PDE5AMAPTESR2HSD17B10ALDH1A1 | |
| SCHEMBL9700689 | 0.74 | RAB9A (0.33) | MOGAT2PDE5AMAPTHSD17B10ALDH1A1 | |
| SCHEMBL9526401 | 0.73 | PTPN1 (0.36) | CYP2C9MOGAT2MAPTHSD17B10GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |