Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527584 | 0.90 | LMNA (0.43) | MAPTALDH1A1MAPK1HPGDLTA4H | |
| SCHEMBL9529174 | 0.88 | LTA4H (0.39) | MAPTALDH1A1HPGDLTA4HL3MBTL1 | |
| SCHEMBL9529759 | 0.87 | KMT2A (0.43) | MAPTMGLLDRD3SMN1; SMN2LMNA | |
| SCHEMBL9529710 | 0.83 | RAB9A (0.44) | MAPTALDH1A1MAPK1HPGDATM | |
| SCHEMBL9529601 | 0.78 | SLC2A1 (0.42) | ALDH1A1SLC2A1L3MBTL1KDM4ECYP11B1 | |
| SCHEMBL9530556 | 0.77 | MAPT (0.43) | MAPTALDH1A1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL9529148 | 0.76 | GLA (0.45) | MAPTALDH1A1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9532132 | 0.74 | KMT2A (0.51) | ALDH1A1MGLLCYP2C9KMT2AKDM4E | |
| SCHEMBL10406688 | 0.73 | ALDH1A1 (0.60) | MAPTALDH1A1MAPK1DRD3HPGD | |
| SCHEMBL9529150 | 0.73 | CYP4F2 (0.41) | MAPTALDH1A1HPGDL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |