Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530566 | 0.83 | MAPK1 (0.46) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9529407 | 0.81 | TDP1 (0.39) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL23803107 | 0.81 | LMNA (0.49) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL8485314 | 0.80 | CUL4A (0.44) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL8603603 | 0.77 | MAPT (0.39) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10578397 | 0.76 | PPOX (0.52) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9836900 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9530530 | 0.74 | LMNA (0.66) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10440379 | 0.73 | TRPA1 (0.45) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL1573655 | 0.73 | SCN9A (0.34) | ALDH1A1KDM4ESMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371240-B1 | USE OF N-PHENYL-SUBSTITUTED OXAZINDIONES AS HERBICIDES AND N-PHENYL-SUBSTITUTED OXAZINDIONES AND SOME PROCESSES FOR THEIR PRODUCTION | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5164498-A | Herbicidal N-phenyl-substituted oxazinediones | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-17 | — | — | US | disclosed |
| US-5061310-A | HERBICIDAL N-PHENYL-SUBSTITUTED OXAZINEDIONES AND OXAZINONETHIONES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| EP-0371240-A1 | Use of N-phenyl-substituted oxazindiones as herbicides and N-phenyl-substituted oxazindiones and some processes for their production | BAYER AG (DE) | 1990-06-06 | — | — | EP | disclosed |
| EP-0290902-A2 | Condensed (thio)hydantoins | BAYER AG (DE) | 1988-11-17 | — | — | EP | disclosed |