SCHEMBL9530637

SCHEMBL9530637

C#CCOc1cc(-c2nn(C)c(S(C)(=O)=O)c2Br)c(F)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.34
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9531683 0.96 PGK1 (0.32) PGK1
SCHEMBL9531431 0.91 KIT (0.31)
SCHEMBL8356733 0.90 PGK1 (0.35) PGK1
SCHEMBL8031283 0.90 PGK1 (0.35) PGK1
SCHEMBL9533882 0.84 PTGDR2 (0.38)
SCHEMBL9696394 0.81 RORC (0.31)
SCHEMBL8177322 0.78 PGK1 (0.35) PGK1
SCHEMBL7506362 0.77 PTGS2 (0.30)
SCHEMBL9696171 0.77 KDM4E (0.34)
SCHEMBL9530862 0.77 PPOX (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542872-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1993-05-26 EP claimed
WO-1992002509-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1992-02-20 WO claimed
WO-1992002509-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1992-02-20 WO disclosed