SCHEMBL9533882

SCHEMBL9533882

Cn1nc(-c2cc(OCC(=O)O)c(Cl)cc2F)c(Br)c1S(C)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 10/20 0.38
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.34
PTGDR Q13258 3/20 0.34
PKM P14618 2/20 0.34
ACLY P53396 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9534173 0.90 PTGDR2 (0.39) PTGDR2TDP1TSHRCYP2C19PTGDR
SCHEMBL9696394 0.85 RORC (0.31) TDP1
SCHEMBL9530637 0.84 PGK1 (0.34)
SCHEMBL9696171 0.83 KDM4E (0.34) PTGDR2TSHR
SCHEMBL9531683 0.81 PGK1 (0.32)
SCHEMBL9530763 0.79 PPOX (0.38)
SCHEMBL7506362 0.77 PTGS2 (0.30)
SCHEMBL6909703 0.77 PKM (0.44) PTGDR2TDP1TSHRCYP2C19PKM
SCHEMBL9530862 0.77 PPOX (0.35) TSHR
SCHEMBL27505317 0.76 TDP1 (0.37) PTGDR2TDP1TSHRCYP2C19PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542872-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1993-05-26 EP claimed
WO-1992002509-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1992-02-20 WO claimed
EP-0542872-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1993-05-26 EP disclosed
WO-1992002509-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1992-02-20 WO disclosed