Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.44 |
| ▸ | HTR1B | P28222 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576624 | 0.81 | DRD2 (0.48) | DRD2HTR1ADRD4SIGMAR1KDM4E | |
| SCHEMBL9536817 | 0.79 | DRD2 (0.48) | DRD2HTR1ADRD4SIGMAR1KDM4E | |
| SCHEMBL3847417 | 0.76 | DRD2 (0.41) | HTR1DHTR1BDRD2HTR1ADRD4 | |
| SCHEMBL9531082 | 0.75 | SIGMAR1 (0.57) | DRD2HTR1ASIGMAR1 | |
| SCHEMBL9529720 | 0.75 | SIGMAR1 (0.57) | HTR1DDRD2HTR1ASIGMAR1 | |
| SCHEMBL9530704 | 0.75 | SIGMAR1 (0.40) | HTR1DDRD2DRD4SIGMAR1 | |
| SCHEMBL9532157 | 0.75 | SIGMAR1 (0.54) | HTR1DHTR1BHTR1ASIGMAR1KDM4E | |
| SCHEMBL3554023 | 0.75 | DRD2 (0.43) | DRD2HTR1ADRD4SIGMAR1KDM4E | |
| SCHEMBL2395487 | 0.73 | DRD2 (0.59) | DRD2HTR1ADRD4LMNA | |
| SCHEMBL3436391 | 0.73 | KDM4E (0.45) | DRD2HTR1ASIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |