SCHEMBL9532464

SCHEMBL9532464

C[C@H](Nc1cc(-c2nn(C)c(S(C)(=O)=O)c2Cl)c(F)cc1Cl)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
SCN1A P35498 1/20 0.30
SCN5A Q14524 1/20 0.30
SCN8A Q9UQD0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696175 1.00 ALDH1A1 (0.34) ALDH1A1CA1CA2SCN1ASCN5A
SCHEMBL9530884 0.88 KAT2B (0.35) SCN1ASCN5ASCN8A
SCHEMBL9533313 0.82 PPOX (0.37)
SCHEMBL9530920 0.80 PDK1 (0.36) ALDH1A1
SCHEMBL31415286 0.80 PDK1 (0.36) ALDH1A1
SCHEMBL9529358 0.80 KDM4E (0.35) ALDH1A1
SCHEMBL7590435 0.79 LMNA (0.38) CA1CA2
SCHEMBL9530417 0.78 RORC (0.31)
SCHEMBL7972198 0.77 NTRK1 (0.34)
SCHEMBL9696185 0.77 NTRK1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542872-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1993-05-26 EP disclosed
WO-1992002509-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1992-02-20 WO disclosed