Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532873 | 0.73 | KMT2A (0.46) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL9533375 | 0.72 | PKM (0.44) | MEN1KMT2APKMRXFP1ALDH1A1 | |
| SCHEMBL9521763 | 0.69 | PKM (0.70) | PKMALDH1A1POLBSMN1; SMN2NPC1 | |
| SCHEMBL1466881 | 0.67 | MEN1 (0.58) | MEN1KMT2ALOXL2ALDH1A1KDM4E | |
| SCHEMBL2540291 | 0.66 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL9096195 | 0.64 | LOXL2 (0.53) | MEN1KMT2ALOXL2HTR6 | |
| SCHEMBL29277536 | 0.62 | HTR6 (0.43) | MEN1KMT2AALDH1A1KDM4EHTR6 | |
| SCHEMBL27658693 | 0.61 | PKM (0.60) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL6947637 | 0.60 | ALDH1A1 (0.48) | MEN1KMT2APKMALDH1A1KDM4E | |
| SCHEMBL3482423 | 0.60 | HTR6 (0.45) | KMT2APKMALDH1A1KDM4EHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238059-B1 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4971971-A | FUNGICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| US-4866064-A | AGRICULTURE HORTICULTURE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0282635-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0238059-A2 | 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |