SCHEMBL3482423

SCHEMBL3482423

Cc1nsc(S(=O)(=O)c2ccccc2)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.45
HTT P42858 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 7/20 0.40
KDM4E B2RXH2 4/20 0.40
MAPT P10636 2/20 0.40
PAX8 Q06710 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
KMT2A Q03164 2/20 0.39
PIK3CA P42336 1/20 0.38
PIK3C3 Q8NEB9 1/20 0.38
PKM P14618 3/20 0.38
HSD17B10 Q99714 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7214866 0.79 ADORA3 (0.50) HTR6HTTL3MBTL1ALDH1A1KDM4E
SCHEMBL8075141 0.76 ADORA3 (0.50) HTTL3MBTL1ALDH1A1KDM4EMAPT
SCHEMBL14755635 0.73 ADORA3 (0.48) HTTALDH1A1KDM4EMAPTPAX8
SCHEMBL7513504 0.72 FAAH (0.42) L3MBTL1ALDH1A1KDM4EMAPTKMT2A
SCHEMBL14755439 0.71 CYP3A4 (0.44) HTTL3MBTL1ALDH1A1KDM4EMAPT
SCHEMBL3475966 0.71 ALDH1A1 (0.54) ALDH1A1KDM4EKEAP1KMT2APKM
SCHEMBL14755500 0.70 PAX8 (0.40) HTTALDH1A1KDM4EMAPTPAX8
SCHEMBL14755716 0.70 CYP3A4 (0.44) HTTALDH1A1KDM4EMAPTPAX8
SCHEMBL1095059 0.69 APOBEC3G (0.44) ALDH1A1KDM4EKMT2AHSD17B10TDP1
SCHEMBL14755599 0.69 GAA (0.48) HTTALDH1A1MAPTKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7740995-B2 Azo compound, colored curable composition, color filter and manufacturing method therefor FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20070037076-A1 Pyrimidine azo dye, curable tri- or higher-functional (meth)acrylic ester monomers, alkali-soluble (meth)acrylic resin binder, photoinitiators ( traizines, benzophenones, lophine dimer etc.); curing, developing; for forming a color filter for use in a liquid crystal display FUJI PHOTO FILM CO., LTD. 2007-02-15 US disclosed