Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370582 | 0.85 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL1408779 | 0.78 | GNAI3 (0.33) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL28768405 | 0.78 | GNAI3 (0.37) | GNAI3GNAO1GNAI1 | |
| SCHEMBL8460971 | 0.77 | SIGMAR1 (0.33) | SIGMAR1GNAI3GNAO1GNAI1FDPS | |
| SCHEMBL4559646 | 0.73 | GNAI3 (0.34) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL812845 | 0.73 | OPRD1 (0.32) | SIGMAR1 | |
| SCHEMBL16719167 | 0.72 | CA2 (0.32) | — | |
| SCHEMBL3388002 | 0.71 | SIGMAR1 (0.31) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL1306135 | 0.71 | GNAI3 (0.31) | GNAI3GNAO1GNAI1 | |
| SCHEMBL1408743 | 0.71 | SIGMAR1 (0.31) | SIGMAR1GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290862-B1 | Process for the preparation of 1,4-diazabicyclo[2.2.2] octanes | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | disclosed |
| EP-0263463-B1 | Process for the preparation of 1,4-diazabicyclo[2,2,2] octanes | BASF Aktiengesellschaft (DE) | 1992-03-25 | — | — | EP | disclosed |
| EP-0310689-A1 | Process for the preparation of 1,4-diazabicyclo(2,2,2)-octanes | BASF Aktiengesellschaft (DE) | 1989-04-12 | — | — | EP | disclosed |
| US-4804758-A | FROM HETEROCYCLIC AMINES USING BORON OR IRON SILICATE ZEOLITE CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| EP-0290862-A2 | Process for the preparation of 1,4-diazabicyclo[2.2.2] octanes | BASF Aktiengesellschaft (DE) | 1988-11-17 | — | — | EP | disclosed |
| EP-0263463-A2 | Process for the preparation of 1,4-diazabicyclo[2,2,2] octanes | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |