Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799757 | 0.89 | LMNA (0.51) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL8799762 | 0.79 | MEN1 (0.39) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9532579 | 0.76 | RAB9A (0.37) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9645999 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KMT2ASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9755465 | 0.76 | HSD11B1 (0.36) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9533252 | 0.75 | HTT (0.35) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9786414 | 0.74 | LMNA (0.34) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL10653073 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMAPTPKM | |
| SCHEMBL10665838 | 0.74 | CTSV (0.46) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9530946 | 0.73 | MME (0.36) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2149572-A | — | — | None | — | — | JP | disclosed |
| EP-0313091-B1 | AMIDE DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF, AND AGRICULTURAL-HORTICULTURAL FUNGICIDE CONTAINING THEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5104886-A | Syntergistic mixtures of amide substituted thiazoles and other fungicides | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-04-14 | — | — | US | disclosed |
| US-4980363-A | CONTROLLING PLANT DISEASES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-12-25 | — | — | US | disclosed |
| JP-H02149572-A | NEW AMIDE DERIVATIVE, ITS PRODUCTION AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE CONTAINING THE SAME | MITSUI TOATSU CHEM INC | 1990-06-08 | — | — | JP | disclosed |
| EP-0313091-A2 | Amide derivatives, processes for production thereof, and agricultural-horticultural fungicide containing them | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-04-26 | — | — | EP | disclosed |