Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532125 | 0.83 | KMT2A (0.56) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL10472894 | 0.80 | SLC1A1 (0.56) | L3MBTL1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL4955338 | 0.80 | SLC1A1 (0.56) | L3MBTL1ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL2000769 | 0.79 | L3MBTL1 (0.54) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL23485348 | 0.78 | PTGS2 (0.57) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL20418679 | 0.78 | L3MBTL1 (0.52) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL8215545 | 0.78 | PTGS2 (0.57) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL12216811 | 0.78 | PTGS2 (0.57) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL12674439 | 0.77 | ALDH1A1 (0.58) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL14945154 | 0.77 | LMNA (0.51) | L3MBTL1LMNAALDH1A1MMP8PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252744-B1 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | LILLY CO ELI (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4734498-A | 3β-succinimidoazetidinones as chiral intermediates | ELI LILLY AND COMPANY (US) | 1988-03-29 | — | — | US | disclosed |
| EP-0252744-A2 | 3-Beta-(3,4-disubstituted succinimido)azetidinones | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |