Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534814 | 0.82 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9536282 | 0.81 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9535094 | 0.73 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL9533864 | 0.72 | ADRA2A (0.56) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL27364470 | 0.68 | CCR6 (0.55) | L3MBTL1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL9533677 | 0.66 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Carbamic Acid SCHEMBL29254315 | 0.65 | CCR6 (0.51) | L3MBTL1ALDH1A1KMT2AKDM4E | |
| SCHEMBL11179486 | 0.64 | POLB (0.45) | L3MBTL1TMEM97SIGMAR1CHRM5CHRM1 | |
| SCHEMBL8900957 | 0.64 | CCR6 (0.51) | L3MBTL1ALDH1A1HSD17B10POLB | |
| SCHEMBL13687190 | 0.63 | LMNA (0.62) | L3MBTL1PTGDR2ALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384677-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-12-01 | — | — | EP | disclosed |
| EP-0384677-A1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-08-29 | — | — | EP | disclosed |