Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727263 | 0.84 | ALDH1A1 (0.48) | HPGDKMT2AKDM4EAPOBEC3AAPOBEC3G | |
| SCHEMBL9538257 | 0.84 | KMT2A (0.49) | HPGDKMT2AOPRM1OPRK1KDM4E | |
| SCHEMBL9536562 | 0.83 | OPRK1 (0.44) | HPGDKMT2AOPRM1OPRK1KDM4E | |
| SCHEMBL9538264 | 0.81 | PLA2G1B (0.38) | HPGDKMT2AOPRM1OPRK1ALDH1A1 | |
| SCHEMBL9538321 | 0.81 | SIGMAR1 (0.49) | HPGDKMT2AOPRM1OPRK1ALDH1A1 | |
| SCHEMBL9536076 | 0.81 | SMN1; SMN2 (0.38) | KMT2AOPRM1OPRK1SMN1; SMN2MEN1 | |
| SCHEMBL9534208 | 0.79 | KMT2A (0.60) | KMT2AKDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL9536709 | 0.79 | OPRK1 (0.36) | HPGDKMT2AOPRM1OPRK1KDM4E | |
| SCHEMBL9535404 | 0.78 | MEN1 (0.38) | KMT2AOPRM1OPRK1KDM4EALDH1A1 | |
| SCHEMBL9539327 | 0.77 | OPRK1 (0.42) | HPGDKMT2AOPRM1OPRK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |