Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534992 | 0.78 | CDC7 (0.54) | CDC7DBF4KCNH2POLBHRH3 | |
| Hydrochloric Acid SCHEMBL9535340 | 0.77 | CDC7 (0.53) | CDC7DBF4KCNH2POLBHRH3 | |
| SCHEMBL9687566 | 0.76 | KCNH2 (0.42) | CDC7DBF4KCNH2LMNAMAPT | |
| SCHEMBL8135558 | 0.74 | KCNH2 (0.45) | CDC7DBF4KCNH2HRH3DRD2 | |
| SCHEMBL10384096 | 0.74 | SLC6A9 (0.43) | KCNH2LMNAMAPTSMN1; SMN2SSTR5 | |
| SCHEMBL17207709 | 0.73 | ACHE (0.35) | LMNAMAPTPOLBSMN1; SMN2HRH3 | |
| SCHEMBL9689825 | 0.73 | CDC7 (0.47) | CDC7DBF4KCNH2HRH3 | |
| SCHEMBL5054675 | 0.73 | NOS2 (0.62) | LMNAMAPTSMN1; SMN2HTTKMT2A | |
| Hydrochloric Acid SCHEMBL9535454 | 0.73 | KCNH2 (0.51) | CDC7DBF4KCNH2HRH3 | |
| SCHEMBL9536746 | 0.72 | KCNH2 (0.46) | CDC7DBF4KCNH2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |