Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465214 | 0.91 | CCR6 (0.52) | CCR6PAX8ALDH1A1HCAR2TDP1 | |
| SCHEMBL28254602 | 0.84 | LMNA (0.44) | ALDH1A1HCAR2TDP1LMNAALOX5 | |
| SCHEMBL3486570 | 0.83 | ALOX5 (0.43) | ALDH1A1TDP1KMT2AL3MBTL1LMNA | |
| SCHEMBL28255715 | 0.81 | CTSK (0.47) | ALDH1A1TDP1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL15330572 | 0.80 | LMNA (0.51) | CCR6PAX8ALDH1A1HCAR2TDP1 | |
| SCHEMBL9537132 | 0.79 | L3MBTL1 (0.44) | TDP1KMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL27811284 | 0.78 | ALDH1A1 (0.45) | CCR6PAX8ALDH1A1HCAR2TDP1 | |
| SCHEMBL13181407 | 0.78 | LTB4R (0.56) | ALDH1A1LTB4RLTB4R2 | |
| SCHEMBL29017859 | 0.78 | ALDH1A1 (0.49) | CCR6PAX8ALDH1A1HCAR2TDP1 | |
| SCHEMBL8383565 | 0.78 | ALDH1A1 (0.49) | CCR6PAX8ALDH1A1HCAR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |