Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114219 | 0.75 | ALDH1A1 (0.48) | ALDH1A1CYP1A2HPGDHSD17B10TDP1 | |
| SCHEMBL1018789 | 0.75 | ALOX5 (0.46) | ALOX5MAOBMAOAMETAP2NPC1 | |
| SCHEMBL103158 | 0.73 | MAOB (0.63) | ALOX5MAOBMAOAMETAP2NPC1 | |
| SCHEMBL30036439 | 0.73 | MAOB (0.63) | ALOX5MAOBMAOAMETAP2NPC1 | |
| SCHEMBL10624403 | 0.73 | ALDH1A1 (0.37) | ALDH1A1CYP1A2HPGDHSD17B10TDP1 | |
| SCHEMBL5485480 | 0.72 | ALDH1A1 (0.41) | ALOX5NPC1RAB9AMAPTKDM4E | |
| SCHEMBL712885 | 0.72 | MAOB (0.49) | ALOX5MAOBMAOAMETAP2NPC1 | |
| SCHEMBL5468830 | 0.72 | MAOB (0.62) | ALOX5MAOBMAOAMETAP2NPC1 | |
| SCHEMBL30956969 | 0.72 | MAOB (0.62) | ALOX5MAOBMAOAMETAP2NPC1 | |
| SCHEMBL542790 | 0.71 | NPC1 (0.42) | ALOX5MAOBMAOAMETAP2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544696-A1 | HYPOGLYCEMIC HYDROXYUREA DERIVATIVES. | PFIZER HOSPITAL PROD (US) | 1993-06-09 | — | — | EP | disclosed |