Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.35 |
| ▸ | HK1 | P19367 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GRK6 | P43250 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567738 | 0.85 | APEX1 (0.39) | APEX1LIG1HK1HKDC1CYP2C19 | |
| SCHEMBL9532418 | 0.82 | MEN1 (0.34) | APEX1CYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL9531607 | 0.79 | VCAM1 (0.34) | APEX1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9531453 | 0.77 | PTGS2 (0.33) | CYP2C19KMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL9530335 | 0.75 | MAPT (0.35) | CYP2C19KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL9533018 | 0.75 | KDM4E (0.35) | ALDH1A1 | |
| SCHEMBL7590435 | 0.71 | LMNA (0.38) | — | |
| SCHEMBL27524947 | 0.71 | MITF (0.32) | APEX1 | |
| SCHEMBL9534173 | 0.71 | PTGDR2 (0.39) | CYP2C19ALDH1A1TDP1 | |
| SCHEMBL9538152 | 0.70 | ALDH1A1 (0.33) | CYP2C19KMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |