Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530503 | 0.90 | TXNRD1 (0.37) | TDP1ALDH1A1SIRT6RPS6KA3CYP1A2 | |
| SCHEMBL9532418 | 0.88 | MEN1 (0.34) | TDP1ALDH1A1CYP1A2CYP2C19MEN1 | |
| SCHEMBL9531607 | 0.84 | VCAM1 (0.34) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL9530563 | 0.84 | PTGS2 (0.39) | PTGS2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8566841 | 0.83 | ALDH1A1 (0.35) | TDP1ALDH1A1SIRT6RPS6KA3CYP1A2 | |
| SCHEMBL9530335 | 0.81 | MAPT (0.35) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8569813 | 0.78 | ALDH1A1 (0.35) | TDP1ALDH1A1SIRT6CYP1A2CYP2C19 | |
| SCHEMBL9537862 | 0.77 | APEX1 (0.38) | TDP1ALDH1A1CYP2C19MEN1KMT2A | |
| SCHEMBL27524947 | 0.76 | MITF (0.32) | MAPTHTTSMN1; SMN2 | |
| SCHEMBL9530862 | 0.75 | PPOX (0.35) | PTGS2ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |